Pre_GI Gene

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Host: NC_007618 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007618:526400 Brucella melitensis biovar Abortus 2308 chromosome I, complete

Host Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
526400527236837ribonuclease IIIQuickGO ontologyBLASTP
5277735296411869Polysaccharide biosynthesis protein CapDQuickGO ontologyBLASTP
5296285306351008Glycosyl transferase family 4QuickGO ontologyBLASTP
531844532431588Bacterial regulatory protein LacI HTH motifQuickGO ontologyBLASTP
533445533747303transposaseQuickGO ontologyBLASTP
533719534168450Integrase catalytic domainQuickGO ontologyBLASTP
534504535283780Formyl transferase N-terminalQuickGO ontologyBLASTP
535310536164855perosamine synthetase WbkBQuickGO ontologyBLASTP
536161536919759ATPGTP-binding site motif A P-loopABC transporterAAA ATPaseQuickGO ontologyBLASTP
536916537698783ABC transporter family 2Acriflavin resistance proteinQuickGO ontologyBLASTP
5377135388161104DegTDnrJEryC1StrS aminotransferaseQuickGO ontologyBLASTP
5388245399121089Short-chain dehydrogenasereductase SDRGDP-mannose 46-dehydrataseQuickGO ontologyBLASTP
540431540859429ISBm1 transposase orfAQuickGO ontologyBLASTP
540778541152375transposaseQuickGO ontologyBLASTP
541182541568387transposaseQuickGO ontologyBLASTP
541565541975411transposaseQuickGO ontologyBLASTP
542067542378312IS711 transposase orfAQuickGO ontologyBLASTP
542410542802393Transposase IS4QuickGO ontologyBLASTP
542803543042240transposaseQuickGO ontologyBLASTP
5431735442911119Glycosyl transferase group 1QuickGO ontologyBLASTP
544349544717369IS5 family element transposase orfAQuickGO ontologyBLASTP
544813545154342IS5 family element transposase orfBQuickGO ontologyBLASTP
545961546389429ISBm1 transposase orfAQuickGO ontologyBLASTP
546308546724417Transposase IS4QuickGO ontologyBLASTP
547084547383300transposaseQuickGO ontologyBLASTP
5476155489041290PhosphoglucomutasephosphomannomutasePhosphoglu c omutasephosphomannomutase alphabetaalpha domain IPhosphoglucomutasephosQuickGO ontologyBLASTP
5489755503991425Mannose-6-phosphate isomerase type IINucleotidyl transferaseMannose-1-phosphate guanylyltransferasemannose-6-phosphate isQuickGO ontologyBLASTP
5516875527961110Glycosyl transferase group 1QuickGO ontologyBLASTP