Pre_GI Gene

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Host: NC_007618 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007618:1593886 Brucella melitensis biovar Abortus 2308 chromosome I, complete

Host Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
159388615948901005Bacterial inner-membrane translocatorVoltage-dependent potassium channelQuickGO ontologyBLASTP
159498615964461461ATPGTP-binding site motif A P-loopABC transporterAAA ATPaseQuickGO ontologyBLASTP
15966261596763138hypothetical proteinBLASTP
15967601597077318hypothetical proteinBLASTP
159747915990951617Glucose-methanol-choline oxidoreductaseGMC oxidoreductaseQuickGO ontologyBLASTP
1603124160319976tRNA-AlaQuickGO ontologyBLASTP
16057971606618822Bacterial regulatory proteins IclR familyQuickGO ontologyBLASTP
160673616081871452Aldehyde dehydrogenaseQuickGO ontologyBLASTP
16083041608894591hypothetical proteinBLASTP
16090071609525519Basic helix-loop-helix dimerization domain bHLHQuickGO ontologyBLASTP
16095421610114573HNH endonucleaseHNH nucleaseQuickGO ontologyBLASTP
1610111161020393hypothetical proteinBLASTP
16102651610372108hypothetical proteinBLASTP
16103881611086699HhH-GPDQuickGO ontologyBLASTP
16111081611983876Glutamyl-tRNA synthetase class IcAminoacyl-tRNA synthetase class IQuickGO ontologyBLASTP
161212616143122187Malate synthaseATPGTP-binding site motif A P-loopMalate synthase GQuickGO ontologyBLASTP
16146171615111495GCN5-related N-acetyltransferaseQuickGO ontologyBLASTP
16151701616081912Sigma-70 factor familySigma-70 region 2Sigma-70 region 4QuickGO ontologyBLASTP
161651216175161005Prenyl group binding site CAAX boxRNA-binding S4Pseudouridine synthasePseudouridine synthase RluPseudouridine synthaseQuickGO ontologyBLASTP