Pre_GI Gene

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Host: NC_007613 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007613:1353500 Shigella boydii Sb227, complete genome

Host Lineage: Shigella boydii; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic that took place in China in the 1950s. Causes dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. Shigella boydii is uncommon except in India, where it was first isolated. Progression to clinical dysentery occurs in most patients infected with this organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
1353504135370119850S ribosomal subunit protein AQuickGO ontologyBLASTP
1353754135408633350S ribosomal subunit protein L20QuickGO ontologyBLASTP
13545611355544984phenylalanine tRNA synthetase alpha-subunitQuickGO ontologyBLASTP
135555913579462388phenylalanine tRNA synthetase beta-subunitQuickGO ontologyBLASTP
13579511358250300integration host factor alpha subunitQuickGO ontologyBLASTP
13590331359398366IS2 ORF1QuickGO ontologyBLASTP
13594221360261840IS2 ORF2QuickGO ontologyBLASTP
136060413637233120hypothetical proteinBLASTP
13639721364892921putative bacteriophage late gene regulatorQuickGO ontologyBLASTP
136523913664231185putative tail sheath proteinQuickGO ontologyBLASTP
13664231366743321putative tail tube proteinQuickGO ontologyBLASTP
13671211367363243putative tail proteinQuickGO ontologyBLASTP
136751413703212808putative tail proteinQuickGO ontologyBLASTP
13703341370822489putative tail proteinQuickGO ontologyBLASTP
13708511371450600putative DNA-invertaseQuickGO ontologyBLASTP
13722291372762534putative tail fiber assembly proteinQuickGO ontologyBLASTP
13727911373354564putative tail fiber assembly proteinQuickGO ontologyBLASTP
137332313754732151putative bacteriophage tail proteinQuickGO ontologyBLASTP
13754761376006531putative phage tail proteinQuickGO ontologyBLASTP
13759991376895897probable phage baseplate assembly proteinQuickGO ontologyBLASTP
13768991377228330phage baseplate assembly proteinQuickGO ontologyBLASTP
13772461377812567putative phage baseplate assembly proteinQuickGO ontologyBLASTP
13778241378459636putative phage tail completion proteinQuickGO ontologyBLASTP
13784521378919468putative phage tail proteinQuickGO ontologyBLASTP