Pre_GI Gene

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Host: NC_007333 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007333:537292 Thermobifida fusca YX, complete genome

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5372925407743483similar to ATPase involved in chromosome partitioningQuickGO ontologyBLASTP
5407715432542484ATPaseQuickGO ontologyBLASTP
5439925456141623hypothetical proteinBLASTP
545701546351651hypothetical proteinBLASTP
5463515475231173similar to Cell wall-associated hydrolase invasion-associated proteinsQuickGO ontologyBLASTP
548778549227450hypothetical protein
549423549740318regulatory protein GntR HTHQuickGO ontologyBLASTP
550441550815375hypothetical proteinBLASTP
5509185520241107putative serine protease precursorQuickGO ontologyBLASTP
5522605543952136putative peptidaseQuickGO ontologyBLASTP
554504555364861hypothetical proteinBLASTP
555449555973525hypothetical protein
555909556760852putative peptidaseQuickGO ontologyBLASTP
5568605581941335hypothetical protein