Pre_GI Gene

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Host: NC_007333 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007333:39579 Thermobifida fusca YX, complete genome

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3957940034456hypothetical protein
4015040398249hypothetical protein
4065441022369hypothetical protein
4120241438237hypothetical proteinBLASTP
4174941982234hypothetical proteinBLASTP
4228642519234hypothetical proteinBLASTP
4281543180366hypothetical protein
43435444931059aspartate-semialdehyde dehydrogenase USG-1 relatedQuickGO ontologyBLASTP
44490457611272aspartate kinaseQuickGO ontologyBLASTP
4598346582600recombination protein RecRQuickGO ontologyBLASTP
4668247032351Conserved hypothetical protein 103QuickGO ontologyBLASTP
47324491621839hypothetical proteinBLASTP
49207527733567DNA polymerase III subunit alphaQuickGO ontologyBLASTP
5307453409336hypothetical protein
5344053640201hypothetical protein
53663550181356conserved hypothetical protein with similarity to AbiLI abortive phage resistance proteinQuickGO ontologyBLASTP
55183572612079DNA polymerase III subunits gamma and tauQuickGO ontologyBLASTP
5889359519627hypothetical proteinBLASTP
59730607611032hypothetical protein
60758623741617hypothetical protein
6282663449624hypothetical proteinBLASTP
63613658412229Tyrosine protein kinaseWD-40 repeatSerinethreonine protein kinaseQuickGO ontologyBLASTP
65942675491608putative regulatory proteinQuickGO ontologyBLASTP
6765268626975putative agmatinaseQuickGO ontologyBLASTP
68727702351509putative transporterQuickGO ontologyBLASTP
70512719091398putative oxidoreductase oxygen dependent FAD-dependent proteinQuickGO ontologyBLASTP
71944741542211helicase C-terminalDEADDEAH box helicase N-terminalQuickGO ontologyBLASTP
74123754541332hypothetical proteinBLASTP
75451795214071hypothetical proteinBLASTP