Pre_GI Gene

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Host: NC_007333 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007333:1457000 Thermobifida fusca YX, complete genome

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
145777314591041332hypothetical proteinBLASTP
14591011459532432hypothetical proteinBLASTP
14597121460305594hypothetical proteinBLASTP
14603361460506171hypothetical proteinBLASTP
146148014626701191cytochrome P450 monooxygenaseQuickGO ontologyBLASTP
14627761463492717hypothetical proteinBLASTP
14638201464572753enoyl-CoA hydrataseisomerase-like proteinQuickGO ontologyBLASTP
14646741465228555maltose O-acetyltransferaseQuickGO ontologyBLASTP
14652561465570315small multidrug resistance protein SMR familyQuickGO ontologyBLASTP
14660421466743702hypothetical protein
146739014686671278CBSQuickGO ontologyBLASTP
14688471469431585hypothetical proteinBLASTP
146976514706438792-hydroxy-3-oxopropionate reductaseQuickGO ontologyBLASTP
14707931471695903helix-turn-helix AraC typeQuickGO ontologyBLASTP
14719421472613672frnE proteinQuickGO ontologyBLASTP
14727051473373669putative secreted cellulose-binding proteinQuickGO ontologyBLASTP
147359114746791089hypothetical proteinBLASTP
147492014759991080alcohol dehydrogenase class IIIQuickGO ontologyBLASTP