Pre_GI Gene

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Host: NC_007333 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007333:1411050 Thermobifida fusca YX, complete genome

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
141105014124411392GTP-binding protein EngAQuickGO ontologyBLASTP
14125821413082501hypothetical proteinBLASTP
14132511414072822archaeal fructose-1 6-bisphosphatase and related enzyme of inositol monophosphatase familyQuickGO ontologyBLASTP
141494514159611017endo-14-beta-xylanaseQuickGO ontologyBLASTP
14163421417124783similar to Molecular chaperone small heat shock proteinQuickGO ontologyBLASTP
141752914190881560methylmalonyl-CoA decarboxylase alpha chainQuickGO ontologyBLASTP
141933514207951461hypothetical proteinBLASTP
14208341421163330putative cyclase IIQuickGO ontology
142120814224701263actinorhodin polyketide beta-ketoacyl synthase alpha subunit 3-oxoacyl-ACP synthase IQuickGO ontologyBLASTP
142246714236751209actinorhodin polyketide beta-ketoacyl synthase beta subunit 3-oxoacyl-ACP synthase IIQuickGO ontologyBLASTP
14237211423981261actinorhodin polyketide synthase acyl carrier protein 3-oxoacyl-ACP synthase acyl carrier proteinQuickGO ontologyBLASTP
14240081424793786ketoacyl reductaseQuickGO ontologyBLASTP
14248191425763945actinorhodin polyketide synthase bifunctional cyclasedehydrataseQuickGO ontologyBLASTP
142579914272141416putative rifampin monooxygenaseQuickGO ontologyBLASTP
14272011427968768putative 3-oxoacyl-acyl-carrier protein reductaseQuickGO ontologyBLASTP
142800614291841179putative cytochrome P450QuickGO ontologyBLASTP
14292131429407195hypothetical proteinBLASTP
142940414306481245putative ferredoxin reductaseQuickGO ontologyBLASTP
143064114324101770putative acyl-CoA carboxylase complex A subunitQuickGO ontologyBLASTP
143240714334411035putative 3-oxoacyl-ACP synthase IIIQuickGO ontologyBLASTP
14334761434111636hypothetical proteinBLASTP
143410814351091002modular polyketide synthaseQuickGO ontologyBLASTP