Pre_GI Gene

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Host: NC_007333 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007333:1129826 Thermobifida fusca YX, complete genome

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
112982611319042079hypothetical proteinBLASTP
11321691132579411hypothetical protein
11326571133409753hypothetical proteinBLASTP
11334891134148660caffeoyl-CoA O-methyltransferaseQuickGO ontologyBLASTP
11341741134887714putative integral membrane proteinQuickGO ontologyBLASTP
11355661136417852methionine aminopeptidaseQuickGO ontologyBLASTP
11364561136680225hypothetical proteinBLASTP
11367291137427699NADPH-dependent F420 reductaseQuickGO ontologyBLASTP
113750211411703669putative DNA methylaseQuickGO ontologyBLASTP
11419961142181186hypothetical proteinBLASTP
11426951142889195hypothetical proteinBLASTP
11428861143740855helix-turn-helix motifQuickGO ontologyBLASTP
11438831144233351hypothetical proteinBLASTP
11442331144709477hypothetical proteinBLASTP
11452231146071849helix-turn-helix motifQuickGO ontologyBLASTP
11462561146600345hypothetical proteinBLASTP
11466001147205606hypothetical proteinBLASTP
114765011486871038putative oxidoreductaseQuickGO ontologyBLASTP
114881611496588433-methyl-2-oxobutanoate hydroxymethyltransferaseQuickGO ontologyBLASTP
114992111512821362glutamine synthetase type IQuickGO ontologyBLASTP
115149711532301734NAD synthaseQuickGO ontologyBLASTP
11532851153740456hypothetical protein
115382511556421818alpha amylase C-terminal all-betaAlpha amylase catalytic subdomainQuickGO ontologyBLASTP
115599511591173123glutamate-ammonia-ligase adenylyltransferaseQuickGO ontologyBLASTP