Pre_GI Gene

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Host: NC_007333 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007333:1 Thermobifida fusca YX, complete genome

Host Lineage: Thermobifida fusca; Thermobifida; Nocardiopsaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Produces thermostable enzymes. Members of this genus are distinguished from most actinomycetes by their ability to form clustered spores that attach directly to the substrate mycelia, and not to the aerial mycelia. Moreover, these bacteria do not produce aerial mycelia at all. M. fusca is the most thermophilic, with some growth detectable at up to 75 degrees C. The natural habitat of Thermobifida is self-heated organic materials, like rotting hay, compost, manure or urban waste piles, etc., which they share with other thermophilic and thermotolerant actinomycetes. Biological and physiological features of these bacteria are accordingly adapted to the conditions of such environments, namely the high temperatures and the presence of abundant plant materials and other bio-polymer substrates of natural origin. Actinomycetes are well suited for this environment because they generally grow as branching hyphae and are well adapted to penetration and degradation of insoluble substrates such as lignocellulose. Spores of Thermobifida are known to cause allergic respiratory diseases called mushroom worker disease and farmer's lung, which develop in agricultural workers who by the nature of their work happen to breathe in significant amounts of actinomycete spores from hay, compost, etc. Some isolates of this organism are able to mineralize plastic disposals and other anthropogenic xenobiotics. Thermobifidaare of particular interest because they produce multiple thermostable enzymes involved in the degradation of lignocellulose.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
19520421848bacterial chromosomal replication initiator protein DnaAQuickGO ontologyBLASTP
282439421119DNA polymerase III subunit betaQuickGO ontologyBLASTP
400248868856-phosphogluconate dehydrogenaseQuickGO ontologyBLASTP
498861211134recombination protein FQuickGO ontologyBLASTP
61116632522hypothetical proteinBLASTP
695089351986DNA topoisomerase IV subunit BQuickGO ontologyBLASTP
8992115382547DNA gyrase subunit AQuickGO ontologyBLASTP
1173812430693hypothetical proteinBLASTP
13759149101152putative transferaseQuickGO ontologyBLASTP
1491715828912n-acetylneuraminate synthaseQuickGO ontologyBLASTP
1590716869963putative glycosyltransferaseQuickGO ontologyBLASTP
16874182021329hypothetical proteinBLASTP