Pre_GI Gene

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Host: NC_007146 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007146:1405459 Haemophilus influenzae 86-028NP, complete genome

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: This nontypeable strain is a clinical isolate from a pediatric patient with otitis media from Columbus Children's Hospital. Causes respiratory tract infections primarily in children. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
140545914068951437pyruvate kinaseQuickGO ontologyBLASTP
140743214086911260prophage CP4-57-like integraseQuickGO ontologyBLASTP
14093051409574270hypothetical proteinBLASTP
14096791409849171hypothetical proteinBLASTP
14098391410372534hypothetical proteinBLASTP
14104441410860417hypothetical proteinBLASTP
14108641411541678hypothetical proteinBLASTP
141156014127231164modification methylase Bsp6I-likeQuickGO ontologyBLASTP
14133291414225897recombination associated proteinQuickGO ontologyBLASTP
141435014156961347hypothetical proteinBLASTP
14157581416192435Single-strand binding proteinQuickGO ontologyBLASTP
14161921416836645hypothetical proteinBLASTP
14168171417737921predicted recombinational DNA repair protein RecE pathwayQuickGO ontologyBLASTP
14177501418043294hypothetical proteinBLASTP
14180401418384345hypothetical proteinBLASTP
14183981419135738modification methylase DpnIIB-likeQuickGO ontologyBLASTP
141922614202571032hypothetical proteinBLASTP
14202471420498252hypothetical proteinBLASTP
14206171420928312hypothetical proteinBLASTP
14213141421499186hypothetical proteinBLASTP
142166014228081149hypothetical proteinBLASTP
14228191423679861hypothetical proteinBLASTP
14237421424107366hypothetical proteinBLASTP
14241091424696588hypothetical proteinBLASTP
14248521425037186hypothetical proteinBLASTP
14250681425496429hypothetical proteinBLASTP
14254971426006510hypothetical proteinBLASTP
14260111426601591hypothetical proteinBLASTP
14265981427233636hypothetical proteinBLASTP
14272181428000783hypothetical proteinBLASTP
14280021428235234hypothetical proteinBLASTP
14282811428733453hypothetical proteinBLASTP
14287771428983207hypothetical proteinBLASTP
14291171430085969hypothetical proteinBLASTP