Pre_GI Gene

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Host: NC_006578 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006578:1 Bacillus thuringiensis serovar konkukian str. 97-27 plasmid

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxin. This organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
604891288hypothetical proteinBLASTP
12552112858hypothetical proteinBLASTP
21032381279hypothetical proteinBLASTP
24382680243hypothetical protein
27563364609hypothetical proteinBLASTP
338945311143possible NLPP60 family proteinQuickGO ontologyBLASTP
453364701938possible ATPaseQuickGO ontologyBLASTP
64857159675hypothetical proteinBLASTP
72167530315hypothetical proteinBLASTP
76017798198hypothetical proteinBLASTP
78038063261hypothetical proteinBLASTP
8081114463366possible membrane proteinQuickGO ontologyBLASTP
11481141142634possible conjugation proteinQuickGO ontologyBLASTP