Pre_GI Gene

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Host: NC_006511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006511:2819128 Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This serovar has a narrow host range and causes a typhoid-like (paratyphoid fever) illness in humans. It is especially prevalent in southern and eastern Asia, and has been associated with some particularly virulent outbreaks. A number of isolates are increasingly antibiotic resistant. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
281912828212062079transcriptional activator of the formate hydrogenlyase systemQuickGO ontologyBLASTP
28212682821612345hypothetical proteinBLASTP
28217942822711918Iron transport protein periplasmic-binding proteinQuickGO ontologyBLASTP
28227082823529822Iron transport protein ATP-binding componentQuickGO ontologyBLASTP
28235262824386861Iron transport protein inner membrane componentQuickGO ontologyBLASTP
28243772825225849Iron transport protein inner membrane componentQuickGO ontologyBLASTP
28251972825406210hypothetical proteinBLASTP
28255022826257756possible AraC-family transcriptional regulatorQuickGO ontologyBLASTP
28266422827529888possible AraC-family transcriptional regulatorQuickGO ontologyBLASTP
28278752828327453hypothetical protein found within S typhi pathogenicity island 1QuickGO ontologyBLASTP
28283432829014672oxygen-regulated invasion proteinQuickGO ontologyBLASTP
28289712829549579oxygen-regulated invasion proteinQuickGO ontologyBLASTP
28295422830300759pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
28302972830602306pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
28306212830863243pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
283088828320661179pathogenicity 1 island effector proteinQuickGO ontologyBLASTP
28323822833311930AraC-family transcriptional regulatorQuickGO ontologyBLASTP
283440228360631662invasion protein regulatorQuickGO ontologyBLASTP
28360812836563483cell invasion proteinQuickGO ontologyBLASTP
283661728382481632stpA-like proteinQuickGO ontologyBLASTP
28382352838585351chaperone associated with virulenceQuickGO ontologyBLASTP
28386542838914261doubtful CDS found within S typhi pathogenicity islandQuickGO ontologyBLASTP
28389582839206249acyl carrier proteinQuickGO ontologyBLASTP
283922528412822058pathogenicity island 1 effector protein function unknownQuickGO ontologyBLASTP
284130128423231023pathogenicity island 1 effector proteinQuickGO ontologyBLASTP
284239328436221230pathogenicity island 1 effector proteinQuickGO ontologyBLASTP
284365028454311782pathogenicity island 1 effector proteinQuickGO ontologyBLASTP
28454342845931498unknown functionQuickGO ontologyBLASTP
284606928471391071type III secretion proteinQuickGO ontologyBLASTP
28471262847917792secretory protein associated with virulenceQuickGO ontologyBLASTP
28479212848181261secretory protein associated with virulenceQuickGO ontologyBLASTP
28482072848881675secretory protein associated with virulenceQuickGO ontologyBLASTP
28488712849782912type III secretion proteinQuickGO ontologyBLASTP
284978228507921011antigen presentation protein SpaNQuickGO ontologyBLASTP
28507922851235444virulence-associated secretory proteinQuickGO ontologyBLASTP
285121328525081296type III secretion system ATPaseQuickGO ontologyBLASTP
28525052852912408virulence-associated secretory proteinQuickGO ontologyBLASTP
285293628549932058possible secretory protein associated with virulenceQuickGO ontologyBLASTP
285501828561361119cell invasion proteinQuickGO ontologyBLASTP
285613328578211689secretory protein associated with virulenceQuickGO ontologyBLASTP
28578182858468651possible AraC-family regulatory proteinQuickGO ontologyBLASTP
28589242859367444cell adheranceinvasion proteinQuickGO ontologyBLASTP
28597622859980219hypothetical proteinBLASTP
28602502860531282hypothetical proteinBLASTP
28605312861055525hypothetical proteinBLASTP
28611282861555428BLASTP
28617822862438657BLASTP
28626082862793186hypothetical proteinBLASTP
28628022863128327hypothetical proteinBLASTP
286328728658542568DNA mismatch repair proteinQuickGO ontologyBLASTP
28659102866224315hypothetical proteinBLASTP
286628728674951209possible membrane transport proteinQuickGO ontologyBLASTP
28676042868515912possible LysR-family transcriptional regulatorQuickGO ontologyBLASTP
286855728700531497possible permeaseQuickGO ontologyBLASTP
28700502871000951hypothetical proteinBLASTP