Pre_GI Gene

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Host: NC_006142 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006142:312000 Rickettsia typhi str. Wilmington, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
3122443142952052ribonuclease EQuickGO ontologyBLASTP
316021316932912Pseudouridine synthaseQuickGO ontologyBLASTP
3170093182621254penicillin binding protein 4QuickGO ontologyBLASTP
318271319056786Ecoli exonuclease IIIQuickGO ontologyBLASTP
319148320128981Pyruvate decarboxylaseQuickGO ontologyBLASTP
320299321279981dihydrolipoamide acetyltransferaseQuickGO ontologyBLASTP
3217623235791818GTP-binding protein TypA tyrosine phosphorylated protein AQuickGO ontologyBLASTP
324421324927507hypothetical proteinBLASTP
3250363264871452isocitrate dehydrogenaseQuickGO ontologyBLASTP
326584326904321hypothetical proteinBLASTP
3270043280501047hypothetical proteinBLASTP
328031328690660heme exporter protein BQuickGO ontologyBLASTP
328758329216459rickettsial conserved hypothetical proteinQuickGO ontologyBLASTP
329233329766534Complex III mitochondrial electron transportQuickGO ontologyBLASTP
3297733309691197Complex III mitochondrial electron transportQuickGO ontologyBLASTP
331424332179756cytochrome c1 heme protein precursorQuickGO ontologyBLASTP
332686333177492HSP22-like heat shock proteinQuickGO ontologyBLASTP
3334793345011023peptide chain release factor 2QuickGO ontologyBLASTP