Pre_GI Gene

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Host: NC_006142 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006142:262825 Rickettsia typhi str. Wilmington, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2628252645941770ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
264771265040270rickettsial conserved hypothetical proteinQuickGO ontologyBLASTP
2652052665481344cytochrome d ubiquinol oxidase subunit IQuickGO ontologyBLASTP
2666802676991020cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
267959268837879glucosyltransferaseQuickGO ontologyBLASTP
2689762702141239probable mitochondrial proteaseQuickGO ontologyBLASTP
270336271046711phosphoribosylaminoimidazole-succinocarboxamide synthaseQuickGO ontologyBLASTP
2723652742721908threonyl-tRNA synthetaseQuickGO ontologyBLASTP
275036275173138rickettsial conserved hypothetical proteinQuickGO ontology
276535276882348rickettsial conserved hypothetical proteinQuickGO ontologyBLASTP
2769352781311197rickettsial conserved hypothetical proteinQuickGO ontologyBLASTP
2783612797251365outer membrane protein TolC precursorQuickGO ontologyBLASTP
279727280140414hypothetical proteinBLASTP
2802732820331761rickettsial conserved hypothetical proteinQuickGO ontologyBLASTP