Pre_GI Gene

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Host: NC_006085 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006085:854500 Propionibacterium acnes KPA171202, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
854597856093149730S ribosomal protein S1QuickGO ontologyBLASTP
8563138577161404conserved protein putative for Fe-transportQuickGO ontologyBLASTP
8576228589411320hemin receptor precursorQuickGO ontologyBLASTP
8589388599961059ABC-type transporter permease componentQuickGO ontologyBLASTP
859996860775780ABC-type transporter ATPase componentQuickGO ontologyBLASTP
8607998625081710ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
8625058641751671ABC-type transport system fused ATPase and permeaseQuickGO ontologyBLASTP
864204864899696dephospho-CoA kinaseQuickGO ontologyBLASTP
8657328669311200hypothetical proteinBLASTP
867392868213822magnesium-chelatase subunit ChlIQuickGO ontologyBLASTP
8683748701761803magnesium-chelatase subunitQuickGO ontologyBLASTP
870292870708417hypothetical proteinBLASTP
8707448721561413CobNmagnesium chelatase putative subunit HQuickGO ontologyBLASTP
8720038745762574CobNmagnesium chelatase subunitQuickGO ontologyBLASTP
874573875370798ironIII dicitrate transport system permease protein FecEQuickGO ontologyBLASTP
875384876196813ironIII dicitrate transport system permease proteinQuickGO ontologyBLASTP
876424877203780periplasmic binding proteinQuickGO ontologyBLASTP
877356877595240hypothetical protein
877803878078276hypothetical proteinBLASTP
878164878439276ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
878530878811282ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
878852879361510putative permeaseQuickGO ontologyBLASTP
879385879864480hypothetical proteinBLASTP
879902880663762hypothetical protein
880966881247282hypothetical proteinBLASTP
8814228835272106excinuclease ABC subunit BQuickGO ontologyBLASTP
883718884707990membrane spanning protein TerC familyQuickGO ontologyBLASTP
884716885372657Zn-dependent hydrolaseQuickGO ontologyBLASTP
885418886161744hypothetical proteinBLASTP
8863038892722970excinuclease ABC subunit AQuickGO ontologyBLASTP