Pre_GI Gene

Some Help

Host: NC_006085 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006085:234127 Propionibacterium acnes KPA171202, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
234127234828702hypothetical proteinBLASTP
234838235749912hypothetical proteinBLASTP
235924236754831putative RHS related proteinQuickGO ontologyBLASTP
2366962379611266putative RHS-family proteinQuickGO ontologyBLASTP
2379662399211956RHS-family proteinQuickGO ontologyBLASTP
240186241112927hypothetical proteinBLASTP
241522242385864hypothetical proteinBLASTP
243319243765447hypothetical proteinBLASTP
243747244361615hypothetical proteinBLASTP
244591245037447hypothetical proteinBLASTP
2450192478802862RHS-family proteinQuickGO ontologyBLASTP
2478862506782793RHS-family proteinQuickGO ontologyBLASTP
250798251520723hypothetical proteinBLASTP
251890252255366putative heat shock proteinQuickGO ontologyBLASTP
252517252894378hypothetical proteinBLASTP
2529622558352874DNA polymerase III subunits gamma and tauQuickGO ontologyBLASTP