Pre_GI Gene

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Host: NC_005957 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005957:4169610 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
41696104170533924cysteine synthaseQuickGO ontologyBLASTP
417061641713116965-methylthioadenosineS-adenosylhomocysteine nucleosidaseQuickGO ontologyBLASTP
41713264171964639hypothetical proteinBLASTP
41721014172316216hypothetical proteinBLASTP
41723524173008657hypothetical proteinBLASTP
417312541748791755penicillin-binding proteinQuickGO ontologyBLASTP
41749724175448477transcription elongation factor GreAQuickGO ontologyBLASTP
41757274176365639uridine kinaseQuickGO ontologyBLASTP
417638341776631281peptidase U32 familyQuickGO ontologyBLASTP
41776824178611930peptidase U32 familyQuickGO ontologyBLASTP
41786194179260642O-methyltransferase possible caffeoyl-CoA O-methyltransferaseQuickGO ontologyBLASTP
417946341805331071probable aminodeoxychorismate lyaseQuickGO ontologyBLASTP
41807514181029279hypothetical proteinBLASTP
41810424181455414Holliday junction resolvase-like proteinQuickGO ontologyBLASTP
41814594181725267hypothetical proteinBLASTP
418180241844442643alanyl-tRNA synthetaseQuickGO ontologyBLASTP
41849274185271345hypothetical proteinBLASTP
418531041863771068probable membrane proteinQuickGO ontologyBLASTP
41865544186766213hypothetical proteinBLASTP
41869494187137189hypothetical proteinBLASTP
418726541896012337exodeoxyribonuclease V alpha subunitQuickGO ontologyBLASTP
41896974190356660TPR domain protein tetratricopeptide repeat family proteinQuickGO ontologyBLASTP
419046741915821116tRNA 5-methylaminomethyl-2-thiouridylate-methyltransferaseQuickGO ontologyBLASTP
419159941927441146aminotransferase class VQuickGO ontologyBLASTP