Pre_GI Gene

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Host: NC_005957 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005957:3746891 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
374689137481981308cell division proteinQuickGO ontologyBLASTP
37485993749369771cell division proteinQuickGO ontologyBLASTP
37494683750373906UDP-N-acetylenolpyruvoylglucosamine reductaseQuickGO ontologyBLASTP
375043537515861152N-acetylglucosaminyl transferaseQuickGO ontologyBLASTP
375163537527261092stage V sporulation protein EQuickGO ontologyBLASTP
375281737541691353UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetaseQuickGO ontologyBLASTP
37541703755144975phospho-N-acetylmuramoyl-pentapeptide- transferaseQuickGO ontologyBLASTP
375516737566421476UDP-N-acetylmuramoylalanyl-D-glutamate--2 6-diaminopimelate ligaseQuickGO ontologyBLASTP
375685137587671917sporulation specific penicillin-binding proteinQuickGO ontologyBLASTP
375884937609992151penicillin-binding proteinQuickGO ontologyBLASTP
37610213761383363cell division proteinQuickGO ontologyBLASTP
37613993762331933S-adenosyl-methyltransferase MraWQuickGO ontologyBLASTP
376270137643171617hypothetical proteinBLASTP
376439737652848882-dehydropantoate 2-reductaseQuickGO ontologyBLASTP
37656333766106474acetyltransferase GNAT familyQuickGO ontologyBLASTP
37661413766647507hypothetical proteinBLASTP
3766777376705527950S ribosomal protein L32QuickGO ontologyBLASTP
37670123767512501hypothetical proteinBLASTP
376772637689071182hypothetical proteinBLASTP
376893737699591023ATP-dependent protease LaQuickGO ontologyBLASTP
37699523770743792patatin-like phospholipaseQuickGO ontologyBLASTP