Pre_GI Gene

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Host: NC_005957 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005957:2756000 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
275611827592433126membrane protein MmpL familyQuickGO ontologyBLASTP
27594882760054567transcriptional regulator TetR familyQuickGO ontologyBLASTP
276036427615361173acetyltransferase GNAT familyQuickGO ontologyBLASTP
2761809276309812903-phosphoshikimate 1-carboxyvinyltransferaseQuickGO ontologyBLASTP
276311527642151101prephenate dehydrogenaseQuickGO ontologyBLASTP
276420827653081101putative aminotransferaseQuickGO ontologyBLASTP
276532627664981173chorismate synthaseQuickGO ontologyBLASTP
2766781276785710773-deoxy-7-phosphoheptulonate synthaseQuickGO ontologyBLASTP
276868927722013513hypothetical proteinBLASTP
27723522772789438hypothetical proteinBLASTP
27729592773465507isochorismataseQuickGO ontologyBLASTP
27735102774043534acetyltransferase GNAT familyQuickGO ontologyBLASTP
27740572774362306hypothetical proteinBLASTP
27744642774979516hypothetical proteinBLASTP
277503127766051575hypothetical proteinBLASTP
27770112777490480probable acetyltransferase GNAT familyQuickGO ontologyBLASTP
277760127790371437probable integral membrane protein possible gluconate transporterQuickGO ontologyBLASTP