Pre_GI Gene

Some Help

Host: NC_005956 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005956:699206 Bartonella henselae str. Houston-1, complete genome

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6992067007051500aspartylglutamyl-tRNA amidotransferase subunit BQuickGO ontologyBLASTP
700897701295399NADH-ubiquinone oxidoreductaseQuickGO ontologyBLASTP
701381701806426hypothetical proteinBLASTP
702405703145741hypothetical proteinBLASTP
703135703959825tRNA rRNA methyltransferaseQuickGO ontologyBLASTP
70416370424684tRNA-TyrQuickGO ontologyBLASTP
70427670434974tRNA-GlyQuickGO ontology
7045157056901176elongation factor TuQuickGO ontologyBLASTP
70574670582176tRNA-TrpQuickGO ontologyBLASTP
706032706244213Preprotein translocase secE subunitQuickGO ontologyBLASTP
706265706795531transcription antitermination protein NusGQuickGO ontologyBLASTP
70694570737342950S ribosomal protein L11QuickGO ontologyBLASTP
70737870807669950S ribosomal protein L1QuickGO ontologyBLASTP
70844170895951950S ribosomal protein L10QuickGO ontologyBLASTP
70906270943337250S ribosomal protein L7L12QuickGO ontologyBLASTP
7097227138734152DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
7140497182574209DNA-directed RNA polymerase beta subunitQuickGO ontologyBLASTP
718857719243387Transcriptional regulatorQuickGO ontologyBLASTP
719467720156690NitroreductaseQuickGO ontologyBLASTP
7205107219071398L-serine dehydrataseQuickGO ontologyBLASTP