Pre_GI Gene

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Host: NC_005956 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005956:1139342 Bartonella henselae str. Houston-1, complete genome

Host Lineage: Bartonella henselae; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: Bartonella henselae str. Houston-1 (ATCC 49882) was isolated from human blood in Houston Texas. Causative agent of cat scratch fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was identified as the causative agent of cat scratch fever, a disease found commonly in children or in immunocompromised adults. The proliferation of the vascular endothelium (bacillary angiomatosis) is characterisitic of Bartonella infection and results in multiplication of the bacterium's host cells. Infected macrophages are stimulated to release vascular endothelial growth factor (VEGF) and interleukin 1 beta, both of which promote angiogenesis. Endothelial cells are also stimulated to grow and divide by direct contact with bacterial cells. In addition, programmed cell death (apoptosis) of endothelial cells is inhibited, combatting a common mechanism eukaryotic cells use to deal with bacterial infection. Other pathogenicity factors include pili and outer membrane adhesins for attachment to host cells.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
113934211406611320ATPase aaa familyQuickGO ontologyBLASTP
114067011420611392Serine proteaseQuickGO ontologyBLASTP
1142346114277442950S ribosomal protein L17QuickGO ontologyBLASTP
114279911438121014DNA-directed RNA polymerase alpha subunitQuickGO ontologyBLASTP
1143907114429639030S ribosomal protein S11QuickGO ontologyBLASTP
1144445114481336930S ribosomal protein S13QuickGO ontologyBLASTP
11449951145573579adenylate kinaseQuickGO ontologyBLASTP
114557011469161347preprotein translocase SecYQuickGO ontologyBLASTP
1147081114754546550S ribosomal protein l15QuickGO ontologyBLASTP
1147566114777220750S ribosomal protein l30QuickGO ontologyBLASTP
1147804114835254930S ribosomal protein S5QuickGO ontologyBLASTP
1148470114883236350S ribosomal protein L18QuickGO ontologyBLASTP
1148845114937853450S ribosomal protein L6QuickGO ontologyBLASTP
1149417114981539930S ribosomal protein S8QuickGO ontologyBLASTP
1149830115013530630S ribosomal protein S14QuickGO ontologyBLASTP
1150160115071755850S ribosomal protein L5QuickGO ontologyBLASTP
1150710115102431550S ribosomal protein L24QuickGO ontologyBLASTP
1151037115140536950S ribosomal protein L14QuickGO ontologyBLASTP
1151550115178924030S ribosomal protein S17QuickGO ontologyBLASTP
1151801115200120150S ribosomal protein l29QuickGO ontologyBLASTP
1152014115242741450S ribosomal protein L16QuickGO ontologyBLASTP
1152463115317371130S ribosomal protein S3QuickGO ontologyBLASTP
1153173115356239050S ribosomal protein L22QuickGO ontologyBLASTP
1153565115384327930S ribosomal protein S19QuickGO ontologyBLASTP
1153859115469283450S ribosomal protein L2QuickGO ontologyBLASTP
1154714115500729450S ribosomal protein L23QuickGO ontologyBLASTP
1155004115562462150S ribosomal protein L4QuickGO ontologyBLASTP
1155624115636474150S ribosomal protein L3QuickGO ontologyBLASTP
1156392115670030930S ribosomal protein S10QuickGO ontologyBLASTP
115676611579411176elongation factor TuQuickGO ontologyBLASTP