Pre_GI Gene

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Host: NC_005126 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005126:5188976 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
518897651899891014Transposase IS630 familyQuickGO ontologyBLASTP
51904255190589165
51930385193559522RNA polymerase sigma-70 factorQuickGO ontologyBLASTP
51935615194526966Protein fecRQuickGO ontologyBLASTP
51979365198934999IronIII dicitrate transport system permease protein FecCQuickGO ontologyBLASTP
51989315199887957IronIII dicitrate transport system permease protein FecDQuickGO ontologyBLASTP
51998885200655768IronIII dicitrate transport ATP-binding protein FecEQuickGO ontologyBLASTP
520118152044953315hypothetical proteinBLASTP
520676252081831422hypothetical proteinBLASTP
52086995209061363hypothetical proteinBLASTP
52095475210455909BLASTP