Pre_GI Gene

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Host: NC_005126 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005126:4423964 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
44239644424350387hypothetical protein
44243474424580234hypothetical protein
44245774425014438hypothetical protein
44250114425382372hypothetical protein
44254014426285885hypothetical protein
442629744274751179hypothetical proteinBLASTP
44274624427965504hypothetical proteinBLASTP
44279754428901927hypothetical proteinBLASTP
44292204429654435hypothetical proteinBLASTP
442965144317682118Type III secretion protein SctVQuickGO ontologyBLASTP
44317654432094330Type III secretion protein SctYQuickGO ontologyBLASTP
44320974432462366Type III secretion protein SctXQuickGO ontologyBLASTP
44324594432830372hypothetical proteinBLASTP
44328274433114288hypothetical proteinBLASTP
44330954433967873Type III secretion control protein SctWQuickGO ontologyBLASTP
443439744357191323type III secretion system ATPaseQuickGO ontologyBLASTP
44357194436180462Type III secretion component protein SctOQuickGO ontologyBLASTP
443619244373221131Type III secretion component protein SctPQuickGO ontologyBLASTP
44373194438251933type III secretion proteinQuickGO ontologyBLASTP
44382484438901654Type III secretion component protein SctRQuickGO ontologyBLASTP
44389044439170267Type III secretion component protein SctSQuickGO ontologyBLASTP
44391674439955789Type III secretion component protein SctTQuickGO ontologyBLASTP
443995244410071056Type III secretion component protein SctUQuickGO ontologyBLASTP
44419074442725819hypothetical proteinBLASTP
44428404443673834hypothetical protein
444410744459511845Type III secretion component protein SctCQuickGO ontologyBLASTP
444594844472161269Type III secretion component protein SctDQuickGO ontology
44472164447434219Type III secretion component protein SctEQuickGO ontology
44474184447672255Type III secretion component protein SctFQuickGO ontology