Pre_GI Gene

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Host: NC_005126 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005126:3485330 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
34853303485947618Alpha-ribazole-5-phosphate phosphataseQuickGO ontologyBLASTP
34859883486212225hypothetical protein
34862283486578351hypothetical proteinBLASTP
34873983488144747cobalamin synthaseQuickGO ontologyBLASTP
34881413488686546adenosylcobinamide kinaseQuickGO ontologyBLASTP
34919323492717786precorrin-6x reductaseQuickGO ontologyBLASTP
34927143493439726precorrin-3B C17-methyltransferaseQuickGO ontologyBLASTP
349343334944941062cobalamin biosynthesis protein CbiGQuickGO ontologyBLASTP
34944753495248774Precorrin-4 C11-methyltransferase precorrin-3-methylaseQuickGO ontologyBLASTP
34952413495810570precorrin-8w decarboxylaseQuickGO ontologyBLASTP
34958003496402603precorrin-6B methylaseQuickGO ontologyBLASTP
349639934975351137cobalt-precorrin-6A synthaseQuickGO ontologyBLASTP
34981793499138960cobalamin biosynthesis proteinQuickGO ontologyBLASTP
349913535005171383cobyrinic acid ac-diamide synthaseQuickGO ontologyBLASTP
35046323504922291hypothetical proteinBLASTP
35049223505212291hypothetical proteinBLASTP
35055193505635117hypothetical protein