Pre_GI Gene

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Host: NC_004917 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004917:340997 Helicobacter hepaticus ATCC 51449, complete genome

Host Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
340997341653657hypothetical proteinBLASTP
341634342065432nickel responsive regulatorQuickGO ontologyBLASTP
342217342654438biopolymer transport proteinQuickGO ontologyBLASTP
342657343037381biopolymer transport proteinQuickGO ontologyBLASTP
343003343731729TonB-like proteinQuickGO ontologyBLASTP
343753344163411hypothetical protein
344219344506288hypothetical protein
3445103465882079elongation factor EF-2QuickGO ontologyBLASTP
34660434707146830S ribosomal protein S7QuickGO ontologyBLASTP
34708734747639030S ribosomal protein S12QuickGO ontologyBLASTP
3475683562528685DNA-dependent RNA polymerase beta subunitQuickGO ontologyBLASTP
35640035678038150S ribosomal protein L7L12QuickGO ontologyBLASTP
35680135728348350S ribosomal protein L10QuickGO ontologyBLASTP
35737435807870550S ribosomal protein L1QuickGO ontologyBLASTP
35809535852042650S ribosomal protein L11QuickGO ontologyBLASTP
358550359065516transcription antitermination protein NusGQuickGO ontologyBLASTP
359086359268183translocaseQuickGO ontologyBLASTP