Pre_GI Gene

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Host: NC_004917 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004917:241053 Helicobacter hepaticus ATCC 51449, complete genome

Host Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
240524241060537hypothetical proteinBLASTP
2410532424321380hypothetical proteinBLASTP
242444243232789hypothetical proteinBLASTP
2432372467913555hypothetical proteinBLASTP
246801247781981hypothetical proteinBLASTP
2478722491401269hypothetical proteinBLASTP
2491682530673900hypothetical proteinBLASTP
2531732547291557hypothetical proteinBLASTP
2547222560591338hypothetical protein
256069256437369hypothetical protein
256448257131684hypothetical proteinBLASTP
2571242589141791hypothetical protein
258911259519609hypothetical proteinBLASTP
260339260572234hypothetical protein
260650260802153hypothetical protein
260976261083108hypothetical protein
261105261455351hypothetical protein
261497262198702hypothetical protein
262248262463216hypothetical protein
262472262783312hypothetical protein
263405264250846integraseQuickGO ontologyBLASTP