Pre_GI Gene

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Host: NC_004917 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004917:1323783 Helicobacter hepaticus ATCC 51449, complete genome

Host Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
13237831324319537adenine phosphoribosyltransferaseQuickGO ontologyBLASTP
13243191325080762hypothetical proteinBLASTP
132512013265441425leucyl aminopeptidaseQuickGO ontologyBLASTP
132654513276451101hypothetical proteinBLASTP
13278411328068228hypothetical protein
13280651328511447hypothetical protein
13285081329365858hypothetical proteinBLASTP
1329706133001731230S ribosomal protein S10QuickGO ontologyBLASTP
1330100133065155250S ribosomal protein L3QuickGO ontologyBLASTP
1330663133128662450S ribosomal protein L4QuickGO ontologyBLASTP
1331287133156828250S ribosomal protein L23QuickGO ontologyBLASTP
1331578133240582850S ribosomal protein L2QuickGO ontologyBLASTP
1332416133269728230S ribosomal protein S19QuickGO ontologyBLASTP
1332707133327957350S ribosomal protein L22QuickGO ontologyBLASTP
1333282133399271130S ribosomal protein S3QuickGO ontologyBLASTP
1333996133442142650S ribosomal protein L16QuickGO ontologyBLASTP
1334408133459618950S ribosomal protein L29QuickGO ontologyBLASTP
1334600133486626730S ribosomal protein S17QuickGO ontologyBLASTP
1334863133523136950S ribosomal protein L14QuickGO ontologyBLASTP
1335231133546723750S ribosomal protein L24QuickGO ontologyBLASTP
1335467133601254650S ribosomal protein L5QuickGO ontologyBLASTP
13360331336146114hypothetical protein
1336209133660439630S ribosomal protein S8QuickGO ontologyBLASTP
1336614133715053750S ribosomal protein L6QuickGO ontologyBLASTP
1337166133752235750S ribosomal protein L18QuickGO ontologyBLASTP
1337532133797244130S ribosomal protein S5QuickGO ontologyBLASTP
1337983133838440250S ribosomal protein L15QuickGO ontologyBLASTP
133838113396311251preprotein translocase SecYQuickGO ontologyBLASTP
13396331340391759methionine aminopeptidaseQuickGO ontologyBLASTP
13403941340612219translation initiation factor IF-1QuickGO ontologyBLASTP
1340816134117836330S ribosomal protein S13QuickGO ontologyBLASTP
1341188134158039330S ribosomal protein S11QuickGO ontologyBLASTP
1341591134221762730S ribosomal protein S4QuickGO ontologyBLASTP
134224513432491005DNA-directed RNA polymerase alpha subunitQuickGO ontologyBLASTP
1343264134361435150S ribosomal protein L17QuickGO ontologyBLASTP
134404813456191572hypothetical proteinBLASTP
134566413467851122hypothetical protein