Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:948054 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
947512948057546adenosylcobinamide kinaseQuickGO ontologyBLASTP
948054948797744cobalamin synthaseQuickGO ontologyBLASTP
9488249498941071nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseQuickGO ontologyBLASTP
949972950901930hypothetical proteinBLASTP
950952951122171hypothetical proteinBLASTP
95112795120276tRNA-AsnQuickGO ontologyBLASTP
9513629528191458putative inner membrane proteinQuickGO ontologyBLASTP
95296095303576tRNA-AsnQuickGO ontologyBLASTP
95345695353681hypothetical protein
953533953919387hypothetical proteinBLASTP
953913954239327hypothetical proteinBLASTP
954228954389162hypothetical proteinBLASTP
9544359558891455AMP nucleosidaseQuickGO ontologyBLASTP
956794957657864hypothetical proteinBLASTP
962479962715237hypothetical protein
9709219738812961hypothetical proteinBLASTP
973891974412522hypothetical proteinBLASTP
97895297902776tRNA-AsnQuickGO ontologyBLASTP
979149979322174hypothetical proteinBLASTP
979325979501177hypothetical proteinBLASTP
97957597965076tRNA-AsnQuickGO ontologyBLASTP
979751980548798hypothetical proteinBLASTP
98063798072690tRNA-SerQuickGO ontologyBLASTP
981029981190162hypothetical proteinBLASTP
981317981736420UmuD proteinQuickGO ontologyBLASTP
9817399830071269DNA polymerase IVQuickGO ontologyBLASTP
983453983665213cold shock proteinQuickGO ontologyBLASTP
9841259853091185outer membrane protein S1QuickGO ontologyBLASTP
985960986271312hypothetical proteinBLASTP
986351987046696hypothetical proteinBLASTP
9871209885501431DNA-cytosine methyltransferaseQuickGO ontologyBLASTP
988531989001471patch repair proteinQuickGO ontologyBLASTP
988990989910921hypothetical proteinBLASTP