Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:799810 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
798848799813966putative sugar kinaseQuickGO ontologyBLASTP
7998108008141005putative hydrolaseQuickGO ontologyBLASTP
8008118020821272putative nucleoside permeaseQuickGO ontologyBLASTP
8023368033881053fructose-bisphosphate aldolaseQuickGO ontologyBLASTP
804424804540117hypothetical proteinBLASTP
804905805240336hypothetical proteinBLASTP
805362805778417hypothetical proteinBLASTP
8064198077801362putative proteaseQuickGO ontologyBLASTP
807944808561618hypothetical proteinBLASTP
808586808783198hypothetical proteinBLASTP
80888080897899hypothetical proteinBLASTP
809218809637420hypothetical proteinBLASTP
810444810746303hypothetical proteinBLASTP
810877811377501hypothetical proteinBLASTP
811448812143696hypothetical proteinBLASTP
812113812391279hypothetical proteinBLASTP
812460813062603hypothetical proteinBLASTP
813172813651480hypothetical proteinBLASTP
813719814168450hypothetical proteinBLASTP
814284814727444hypothetical proteinBLASTP
814829815542714hypothetical proteinBLASTP
815696816415720hypothetical proteinBLASTP
8164208185312112hypothetical proteinBLASTP
818542819249708hypothetical proteinBLASTP
819259820143885hypothetical proteinBLASTP
820143820445303hypothetical proteinBLASTP
820714821436723putative two-component system response regulatorQuickGO ontologyBLASTP
8214338228361404putative two-component system sensor kinaseQuickGO ontologyBLASTP
8228368242481413putative transporter proteinQuickGO ontologyBLASTP
8242458273253081putative RND-family transporter proteinQuickGO ontologyBLASTP
8273268304483123putative RND-family transporter proteinQuickGO ontologyBLASTP
8304488316891242putative efflux system proteinQuickGO ontologyBLASTP