Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:4687270 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
46872704688115846putative outer membrane proteinQuickGO ontologyBLASTP
468932346930723750helicase related proteinQuickGO ontologyBLASTP
469311046956472538DEAD-box helicase-related proteinQuickGO ontologyBLASTP
469566046989593300hypothetical proteinBLASTP
46992234699462240hypothetical proteinBLASTP
46995404700415876hypothetical proteinBLASTP
47005774700852276hypothetical protein
47008964701621726hypothetical proteinBLASTP
470202547036531629hypothetical proteinBLASTP
47036614703918258hypothetical proteinBLASTP
47044064705014609hypothetical proteinBLASTP
47053754706286912hypothetical proteinBLASTP
47064974706958462hypothetical proteinBLASTP
47069754707640666hypothetical proteinBLASTP
47079904708763774uxu operon transcriptional regulatorQuickGO ontologyBLASTP
470876447097771014tryptophanyl-tRNA synthetaseQuickGO ontologyBLASTP
47100744710226153hypothetical proteinBLASTP