Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:4661000 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
466133146624311101putative inner membrane proteinQuickGO ontologyBLASTP
466243146635131083putative inner membrane proteinQuickGO ontologyBLASTP
46637194664717999regulatory proteinQuickGO ontologyBLASTP
4666494466657885tRNA-LeuQuickGO ontologyBLASTP
466674246680071266integraseQuickGO ontologyBLASTP
466807046691461077protein kinaseQuickGO ontologyBLASTP
466914346702161074protein kinaseQuickGO ontologyBLASTP
467019146713541164hypothetical proteinBLASTP
46716304672196567phage polarity suppression proteinQuickGO ontologyBLASTP
46722124672451240bacteriophage gene regulatory proteinQuickGO ontologyBLASTP
46724554673315861putative phage capsid proteinQuickGO ontologyBLASTP
46737384674061324phage DNA binding proteinQuickGO ontologyBLASTP
46741624674545384phage immunity repressor proteinQuickGO ontologyBLASTP
46745424674769228hypothetical proteinBLASTP
46747664675086321hypothetical P4 phage proteinQuickGO ontologyBLASTP
46776554677795141hypothetical proteinBLASTP
46778854678034150hypothetical secreted proteinQuickGO ontologyBLASTP
46804644681216753fimbrial chaperone proteinQuickGO ontologyBLASTP
468122146837732553outer membrane fimbrial usher proteinQuickGO ontologyBLASTP