Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:4381724 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
43847074385480774putative dimethyl sulfoxide reductase subunit CQuickGO ontologyBLASTP
43854624386148687hypothetical proteinBLASTP
438623243876321401hypothetical proteinBLASTP
43879364388841906hypothetical proteinBLASTP
43891284389511384hypothetical proteinBLASTP
43894994389696198hypothetical proteinBLASTP
43897194390006288putative GerE family regulatory proteinQuickGO ontologyBLASTP
43900034390878876araC family regulatory proteinQuickGO ontologyBLASTP
43911444391362219hypothetical proteinBLASTP
43916834391976294hypothetical proteinBLASTP
43919734392464492putative acetyltransferaseQuickGO ontologyBLASTP
43927054393457753nonspecific acid phosphatase precursorQuickGO ontologyBLASTP
439430243953361035hypothetical proteinBLASTP
439533343966971365DNA helicaseQuickGO ontologyBLASTP
439669043984891800hypothetical proteinBLASTP
43986584398963306hypothetical proteinBLASTP
43990914399672582hypothetical proteinBLASTP
43997574400314558hypothetical proteinBLASTP
440055944019021344hypothetical proteinBLASTP
44024884403267780hypothetical proteinBLASTP