Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:3910451 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
39104513911116666DNA repair protein RadCQuickGO ontologyBLASTP
3911334391157023750S ribosomal protein L28QuickGO ontologyBLASTP
3911591391175816850S ribosomal protein L33QuickGO ontologyBLASTP
39118563912665810formamidopyrimidine-DNA glycosylaseQuickGO ontologyBLASTP
39126933913172480phosphopantetheine adenylyltransferaseQuickGO ontologyBLASTP
3913181391445812783-deoxy-D-manno-octulosonic-acid transferaseQuickGO ontologyBLASTP
391490339159371035lipopolysaccharide core biosynthesis proteinQuickGO ontologyBLASTP
391593439170581125lipopolysaccharide core biosynthesis proteinQuickGO ontologyBLASTP
39170513917848798lipopolysaccharide core biosynthesis proteinQuickGO ontologyBLASTP
39178893918272384hypothetical proteinBLASTP
39182963918964669hypothetical proteinBLASTP
391902439201031080lipopolysaccharide 16-galactosyltransferaseQuickGO ontologyBLASTP
392010939211221014lipopolysaccharide 13-galactosyltransferaseQuickGO ontologyBLASTP
392114039221501011lipopolysaccharide 12-glucosyltransferaseQuickGO ontologyBLASTP
39221733922871699lipopolysaccharide core biosynthesis proteinQuickGO ontologyBLASTP
39230213923830810lipopolysaccharide core biosynthesis protein RfaZQuickGO ontologyBLASTP
392392939250741146lipopolysaccharide 12-N-acetylglucosaminetransferaseQuickGO ontologyBLASTP
392513139263451215O-antigen ligaseQuickGO ontologyBLASTP
39263853927338954lipopolysaccharide heptosyltransferase-1QuickGO ontologyBLASTP
392733839283841047ADP-heptose-LPS heptosyltransferase IIQuickGO ontologyBLASTP
39283873929319933ADP-L-Glycero-D-mannoheptose-6-epimeraseQuickGO ontologyBLASTP
3929522393071811972-amino-3-ketobutyrate coenzyme A ligaseQuickGO ontologyBLASTP
393072839317531026L-threonine 3-dehydrogenaseQuickGO ontologyBLASTP
393224839332821035putative glycosyl transferaseQuickGO ontologyBLASTP
39332693934231963hypothetical proteinBLASTP
393423539355181284hypothetical proteinBLASTP
393552839370511524phosphoglyceromutaseQuickGO ontologyBLASTP