Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:3112043 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
311204331131281086membrane-bound lytic murein transglycosylase CQuickGO ontologyBLASTP
311334531146011257nucleoside permeaseQuickGO ontologyBLASTP
31172123117919708hypothetical proteinBLASTP
3118025311810076tRNA-PheQuickGO ontologyBLASTP
31193233119442120hypothetical proteinBLASTP
31196513119839189hypothetical proteinBLASTP
31198293120125297hypothetical proteinBLASTP
31205093120775267bacteriocin immunity proteinQuickGO ontologyBLASTP
31210183121296279bacteriocin immunity proteinQuickGO ontologyBLASTP
31216993122202504hypothetical proteinBLASTP
31224613122646186hypothetical proteinBLASTP
31228433123373531hypothetical proteinBLASTP
31233753124001627hypothetical proteinBLASTP
31241373124307171hypothetical proteinBLASTP
31244513124657207possible membrane proteinQuickGO ontologyBLASTP
31246823124909228hypothetical proteinBLASTP
31254353126118684LysR-family transcriptional regulatorQuickGO ontologyBLASTP
31262233126747525hypothetical proteinBLASTP
312675831282571500possible amino acid transport proteinQuickGO ontologyBLASTP
31284663128732267hypothetical proteinBLASTP
312885431301551302putative oxidoreductaseQuickGO ontologyBLASTP
313031731318011485possible aldehyde dehydrogenaseQuickGO ontologyBLASTP
31323173132802486hypothetical proteinBLASTP
31335283134451924hypothetical proteinBLASTP
31344903135209720possible hydrolaseQuickGO ontologyBLASTP
313580831371121305hexuronate transporterQuickGO ontologyBLASTP