Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:3030580 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
302950730305831077hypothetical proteinBLASTP
30305803031323744probable fimbrial chaperone proteinQuickGO ontologyBLASTP
303136430338532490probable outer membrane fimbrial usher proteinQuickGO ontologyBLASTP
30339733034554582probable fimbrial proteinQuickGO ontologyBLASTP
30352733035872600hypothetical proteinBLASTP
30359523036488537outer membrane proteinQuickGO ontologyBLASTP
30372953037693399hypothetical proteinBLASTP
30376933037920228hypothetical proteinBLASTP
30380973038348252endonuclease fragmentQuickGO ontologyBLASTP
30386293039429801hypothetical proteinBLASTP
3039956304002772hypothetical protein
304006230411831122hypothetical proteinBLASTP
30412853041695411hypothetical proteinBLASTP
30418233042026204hypothetical protein
30420303042749720hypothetical proteinBLASTP
30427983043124327hypothetical protein
304368530451481464hypothetical proteinBLASTP
30455923046344753possible lipoproteinQuickGO ontologyBLASTP
30466153047160546isopentenyl-diphosphate delta-isomeraseQuickGO ontologyBLASTP
304723630487531518lysyl-tRNA synthetaseQuickGO ontologyBLASTP