Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:283289 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
282585283292708hypothetical proteinBLASTP
283289283693405rcsF proteinQuickGO ontologyBLASTP
283812284627816putative lipoprotein precursorQuickGO ontologyBLASTP
284666285304639putative ABC transporter permease proteinQuickGO ontologyBLASTP
2853122863431032putative ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
286533287099567hypothetical proteinBLASTP
293014293469456hypothetical proteinBLASTP
2935732948741302alpha-ketoglutarate permeaseQuickGO ontologyBLASTP
294871295194324hypothetical proteinBLASTP
2952392965941356phosphatidylserine synthaseQuickGO ontologyBLASTP
2967092993692661putative acyl-CoA synthetaseQuickGO ontologyBLASTP
299423300103681hypothetical proteinBLASTP
300176300595420thioredoxin 2QuickGO ontologyBLASTP
3007993018361038putative RNA methyltransferaseQuickGO ontologyBLASTP