Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:1623511 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
16235111624074564hypothetical proteinBLASTP
16243321624847516O6-methylguanine-DNA-alkyltransferaseQuickGO ontologyBLASTP
16250011625795795fumarate and nitrate reduction regulatory proteinQuickGO ontologyBLASTP
16259461626893948hypothetical proteinBLASTP
16269481627202255hypothetical proteinBLASTP
162744116284721032hypothetical proteinBLASTP
16285581629160603conserved hypothetical DNA-binding proteinQuickGO ontologyBLASTP
16292041629890687hypothetical proteinBLASTP
16299181630256339hypothetical proteinBLASTP
16303621630919558putative thiol peroxidaseQuickGO ontologyBLASTP
16310181631851834hypothetical proteinBLASTP
163187216338541983invasin-like proteinQuickGO ontologyBLASTP
16339291634774846putative lipoproteinQuickGO ontologyBLASTP
16350771635928852putative transcriptional regulatorQuickGO ontologyBLASTP
163613016374281299hypothetical proteinBLASTP
16376421637878237putative lipoproteinQuickGO ontologyBLASTP
16380071638597591putative transcriptional regulatorQuickGO ontologyBLASTP
16386751639388714oxidoreductaseQuickGO ontologyBLASTP
16394791640348870putative oxidoreductaseQuickGO ontologyBLASTP
16406251641530906putative transcriptional regulatorQuickGO ontologyBLASTP
16416491642578930putative oxidoreductaseQuickGO ontologyBLASTP
164267516442881614periplasmic murein peptide-binding protein MppAQuickGO ontologyBLASTP
16444781645206729hypothetical proteinBLASTP
16451811646146966muconate lactonizing enzyme family proteinQuickGO ontologyBLASTP