Pre_GI Gene

Some Help

Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:1587000 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
158719815887061509putative esteraseQuickGO ontologyBLASTP
15901171590461345hypothetical proteinBLASTP
15913791592140762putative periplasmic amino acid-binding proteinQuickGO ontologyBLASTP
15921471592794648putative ABC amino acid transporter permeaseQuickGO ontologyBLASTP
15928191593550732ABC transporter ATP-binding subunitQuickGO ontologyBLASTP
15935471594227681putative amino acid ABC transporterQuickGO ontologyBLASTP
159436415959141551hypothetical proteinBLASTP
15966031597040438hypothetical proteinBLASTP
15973111597715405putative cytochromeQuickGO ontologyBLASTP
15979581598758801hypothetical proteinBLASTP
159882216027243903ATP-dependent helicase HrpAQuickGO ontologyBLASTP
16029251603530606acyl carrier protein phosphodiesteraseQuickGO ontologyBLASTP
16035271603976450hypothetical proteinBLASTP
16041191604442324putative secreted proteinQuickGO ontologyBLASTP
16044501604641192putative lipoproteinQuickGO ontologyBLASTP