Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:1271500 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
12715991272135537hypothetical proteinBLASTP
12721781273038861hypothetical proteinBLASTP
12731451273435291hypothetical proteinBLASTP
127353212744649336-phosphofructokinase isozymeQuickGO ontologyBLASTP
12747531275511759putative outer membrane proteinQuickGO ontologyBLASTP
12755601276519960putative outer membrane proteinQuickGO ontologyBLASTP
12766621276976315hypothetical proteinBLASTP
12780011278207207hypothetical proteinBLASTP
127853012797531224O-antigen polymeraseQuickGO ontologyBLASTP
128064512825731929threonyl-tRNA synthetaseQuickGO ontologyBLASTP
12825771283119543translation initiation factor IF-3QuickGO ontologyBLASTP
1283215128341219850S ribosomal protein L35QuickGO ontologyBLASTP
1283463128381935750S ribosomal protein L20QuickGO ontologyBLASTP
1283940128398445phenylalanyl-tRNA synthetase operon leader peptideQuickGO ontology
12841211285104984phenylalanyl-tRNA synthetase alpha subunitQuickGO ontologyBLASTP
128512012875072388phenylalanyl-tRNA synthetase beta subunitQuickGO ontologyBLASTP
12875121287811300integration host factor alpha subunitQuickGO ontologyBLASTP
12880141288994981vtamin B12-transporter permeaseQuickGO ontologyBLASTP
12890861289637552putative glutathione peroxidaseQuickGO ontologyBLASTP
12896371290386750vitamin B12-transporter ATPaseQuickGO ontologyBLASTP
12904631290927465putative lipoproteinQuickGO ontologyBLASTP
12912411291954714hypothetical proteinBLASTP
129201612934581443hypothetical proteinBLASTP