Pre_GI Gene

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Host: NC_004557 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004557:2711702 Clostridium tetani E88, complete genome

Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
27117022712568867thioredoxin reductaseQuickGO ontologyBLASTP
27126382712955318thioredoxinQuickGO ontologyBLASTP
271305027143031254hypothetical proteinBLASTP
27144322715343912citG proteinQuickGO ontologyBLASTP
27153602715872513citX proteinQuickGO ontologyBLASTP
271587427169261053citC citrate pro-3S-lyase ligaseQuickGO ontologyBLASTP
271703727185781542citrate lyase alpha chainQuickGO ontologyBLASTP
27186282719515888citrate lyase beta chainQuickGO ontologyBLASTP
27198812720438558fumarate hydrataseQuickGO ontologyBLASTP
27204522721300849fumarate hydrataseQuickGO ontologyBLASTP
272141027226571248methylaspartate ammonia-lyaseQuickGO ontologyBLASTP
272279827242491452glutamate mutase mutEQuickGO ontologyBLASTP
272426527256681404glutamate mutase mutLQuickGO ontologyBLASTP
27257232726136414methylaspartate mutase subunit SQuickGO ontologyBLASTP
27261982727172975transcriptional regulator putative regular for glutamate degradationQuickGO ontologyBLASTP
27273722728097726germination-specific N-acetylmuramoyl-L-alanine amidaseQuickGO ontologyBLASTP
2728171272856339330S ribosomal protein S9QuickGO ontologyBLASTP
2728594272902843550S ribosomal protein L13QuickGO ontologyBLASTP
27291642729910747tRNA pseudouridine synthase AQuickGO ontologyBLASTP
27299132730710798cobalt transport protein cbiQQuickGO ontologyBLASTP
27307232731589867cobalt transport ATP-binding proteinQuickGO ontologyBLASTP
27315742732419846cobalt transport ATP-binding proteinQuickGO ontologyBLASTP
2732496273283734250S ribosomal protein L17QuickGO ontologyBLASTP
27328722733819948DNA-directed RNA polymerase alpha subunitQuickGO ontologyBLASTP
2733894273451462130S ribosomal protein S4QuickGO ontologyBLASTP
2734545273494339930S ribosomal protein S11QuickGO ontologyBLASTP
2734967273533837230S ribosomal protein S13QuickGO ontologyBLASTP
27360972736846750methionine aminopeptidaseQuickGO ontologyBLASTP
27368462737496651adenylate kinaseQuickGO ontologyBLASTP
273751127387881278preprotein translocase SecYQuickGO ontologyBLASTP
2738790273923044150S ribosomal protein L15QuickGO ontologyBLASTP
27394872739963477ribosomal proteinQuickGO ontology
2739960274031936050S ribosomal protein L18QuickGO ontologyBLASTP
2740340274088254350S ribosomal protein L6QuickGO ontologyBLASTP
2740905274130339930S ribosomal protein S8QuickGO ontologyBLASTP
2741535274207754350S ribosomal protein L5QuickGO ontologyBLASTP
2742099274241932150S ribosomal protein L24QuickGO ontologyBLASTP
2742438274280636950S ribosomal protein L14QuickGO ontologyBLASTP
2743317274376044450S ribosomal protein L16QuickGO ontologyBLASTP
27433272743668342ribosomal proteinQuickGO ontology
2743778274444666930S ribosomal protein S3QuickGO ontologyBLASTP