Pre_GI Gene

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Host: NC_003903 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003903:260796 Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: These bacteria are widely distributed in nature, especially in the soil. Well-studied antiobiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
260796261038243hypothetical proteinBLASTP
261236261547312hypothetical protein
2616832630651383hypothetical protein
263311264000690hypothetical protein
264034264486453hypothetical protein
264803265462660putative secreted proteinQuickGO ontologyBLASTP
265459265794336hypothetical proteinBLASTP
265831266202372putative secreted proteinQuickGO ontology
266354266644291hypothetical proteinBLASTP
266719266880162hypothetical proteinBLASTP
266896267342447hypothetical protein
2675562706753120putative large secreted proteinQuickGO ontologyBLASTP
2710602773086249putative large secreted proteinQuickGO ontologyBLASTP
277758278123366hypothetical proteinBLASTP
2793232808641542insertion element is466s transposaseQuickGO ontologyBLASTP
280963281178216hypothetical protein