Pre_GI Gene

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Host: NC_003903 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003903:167825 Streptomyces coelicolor A3(2) plasmid SCP1, complete sequence

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: These bacteria are widely distributed in nature, especially in the soil. Well-studied antiobiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
167825168244420hypothetical proteinBLASTP
168241168684444hypothetical proteinBLASTP
168681169124444hypothetical proteinBLASTP
1691311727423612putative large membrane proteinQuickGO ontologyBLASTP
173067173675609hypothetical protein
173797174033237hypothetical protein
174030174191162hypothetical protein
174205174516312hypothetical protein
175779176534756hypothetical proteinBLASTP
176599177141543hypothetical protein
177213177917705hypothetical proteinBLASTP
178160178438279hypothetical proteinBLASTP
178395178949555hypothetical proteinBLASTP
178957179805849hypothetical proteinBLASTP
179960180511552hypothetical protein
180497180781285hypothetical protein
1810831822221140hypothetical protein
182335183168834putative integraserecombinaseQuickGO ontologyBLASTP
183470183649180hypothetical protein
183646184086441hypothetical protein
184494185051558hypothetical protein
1856581867071050putative atpgtp-binding proteinQuickGO ontology
1867101882301521putative dna primasehelicaseQuickGO ontologyBLASTP
188227188628402hypothetical proteinBLASTP
188734189642909hypothetical protein
1899291914461518putative secreted esteraseQuickGO ontologyBLASTP
191837192337501putative secreted proteinQuickGO ontologyBLASTP
1929441969544011hypothetical proteinBLASTP
196963197466504hypothetical protein
198102198614513hypothetical proteinBLASTP
1986932003541662hypothetical proteinBLASTP