Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:7659639 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
76596397660481843hypothetical proteinBLASTP
76604787660993516regulator fragmentQuickGO ontology
766099076622251236integral membrane proteinQuickGO ontology
76622587662569312hypothetical protein
766263876638551218carboxylaseQuickGO ontologyBLASTP
766385276650031152hypothetical protein
76650007665629630hypothetical proteinBLASTP
76656537666519867hypothetical proteinBLASTP
76665487667036489hypothetical protein
76670847667884801hypothetical proteinBLASTP
766791876689281011hypothetical proteinBLASTP
76690277669404378hypothetical protein
766961876712071590hypothetical proteinBLASTP
76713357672108774DNA ligaseQuickGO ontologyBLASTP
767268776739911305hypothetical protein
76747957675178384hypothetical protein
76756347676473840insertion element transposaseQuickGO ontologyBLASTP
76779967678349354hypothetical proteinBLASTP
76784557678745291hypothetical proteinBLASTP
76787617679582822hypothetical proteinBLASTP
76797557680447693secreted proteinQuickGO ontologyBLASTP
76805287681016489hypothetical proteinBLASTP
768118076829221743hypothetical proteinBLASTP
76829387683453516hypothetical proteinBLASTP
76835467683878333hypothetical protein
768405776857871731membrane proteinQuickGO ontologyBLASTP
76857847686425642hypothetical proteinBLASTP
76865867687302717hypothetical protein
76873057688201897DNA-binding proteinQuickGO ontology
76888367689048213hypothetical protein membrane proteinQuickGO ontology
76896307690454825hypothetical proteinBLASTP
769178176929051125hypothetical proteinBLASTP
769290776949972091O-methyltransferaseQuickGO ontologyBLASTP
769501676962751260hypothetical proteinBLASTP
769626276993603099hypothetical proteinBLASTP
76994477699626180hypothetical proteinBLASTP
76996647699795132hypothetical proteinBLASTP
76998737700322450hypothetical protein
77002617700728468secreted proteinQuickGO ontologyBLASTP
77008037701378576hypothetical proteinBLASTP
77013757702028654hypothetical protein
77020257702585561DNA-binding proteinQuickGO ontology
770263477038871254probable acyl-CoA dehydrogenaseQuickGO ontologyBLASTP