Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:7028165 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
702552670281682643integral membrane proteinQuickGO ontologyBLASTP
70281657028854690ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
70288417029578738ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
70295757030195621lipoproteinQuickGO ontologyBLASTP
703035470316641311two-component sensorQuickGO ontologyBLASTP
703167270327061035integral membrane proteinQuickGO ontology
70327987033637840integral membrane proteinQuickGO ontologyBLASTP
70337297033962234very hypotheticl protein SC4A208QuickGO ontology
703426670356631398integral membrane proteinQuickGO ontology
703578870372241437sugar transferaseQuickGO ontologyBLASTP
70377377038399663secreted proteinQuickGO ontologyBLASTP
70387577039656900integral membrane proteinQuickGO ontology
703969970410541356lipoproteinQuickGO ontologyBLASTP
70416117041910300hypothetical proteinBLASTP
70420547042737684hypothetical proteinBLASTP
70430847043440357hypothetical proteinBLASTP
704372470450671344lipoproteinQuickGO ontology
70466187047526909secreted proteinQuickGO ontologyBLASTP
70484437049126684integral membrane proteinQuickGO ontology
704938270511511770integral membrane lysyl-tRNA synthetaseQuickGO ontologyBLASTP
705152670534601935integral membrane proteinQuickGO ontologyBLASTP
70536327054015384hypothetical proteinBLASTP
70541187054684567hypothetical proteinBLASTP
70549657055324360hypothetical protein
70553217055713393hypothetical protein
705618970572921104integral membrane proteinQuickGO ontologyBLASTP
705780970590261218IS110 transposaseintegraseQuickGO ontologyBLASTP
705910470602431140transposaseQuickGO ontologyBLASTP
706037570618381464transposaseQuickGO ontologyBLASTP
70618357062605771IS element ATP binding proteinQuickGO ontologyBLASTP
70652147065729516hypothetical proteinBLASTP