Pre_GI Gene

Some Help

Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:6568000 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
65680576568779723secreted proteinQuickGO ontology
656877965715922814hypothetical proteinBLASTP
65720326572550519secreted proteinQuickGO ontologyBLASTP
657318665747151530UDP-N-acetylglucosamine transferaseQuickGO ontologyBLASTP
657530565780192715aconitate hydrataseQuickGO ontologyBLASTP
65782366578481246hypothetical proteinBLASTP
65785206578807288hypothetical protein
65787436579171429hypothetical protein
65792136580073861DNA-binding proteinQuickGO ontologyBLASTP
658025665840623807secreted ATPGTP binding proteinQuickGO ontologyBLASTP
658462465860331410lipoproteinQuickGO ontologyBLASTP
658604165871021062probable transmembrane transport proteinQuickGO ontologyBLASTP
65870996588007909probable transmembrane transport proteinQuickGO ontologyBLASTP
658824265894531212probable transcriptional repressor proteinQuickGO ontologyBLASTP
658957565906901116solute-binding proteinQuickGO ontologyBLASTP