Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:6470909 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
647090964734522544probable export proteinQuickGO ontologyBLASTP
64736066474202597probable transcriptional regulatorQuickGO ontologyBLASTP
64743176474436120hypothetical protein
64745176474711195hypothetical protein
64747086474914207hypothetical proteinBLASTP
64749476475291345hypothetical protein
647542664769911566oligopeptide binding proteinQuickGO ontologyBLASTP
647743864800352598probable secreted proteaseQuickGO ontologyBLASTP
648020064814351236probable secreted proteaseQuickGO ontologyBLASTP
64816086482600993probable transcriptional regulatorQuickGO ontologyBLASTP
64828436483358516hypothetical proteinBLASTP
64836756484187513hypothetical proteinBLASTP
64849656485303339hypothetical proteinBLASTP
64869616487272312hypothetical proteinBLASTP
64873216487725405hypothetical proteinBLASTP
648777264892681497probable DEAD-box RNA helicaseQuickGO ontologyBLASTP
64896176489820204cold-shock domain proteinQuickGO ontologyBLASTP
64904626491442981short chain dehydrogenaseQuickGO ontologyBLASTP