Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:56225 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
56225593833159hypothetical proteinBLASTP
5955860241684hypothetical proteinBLASTP
6006960275207hypothetical protein
60740640933354secreted proteinQuickGO ontologyBLASTP
6460564925321hypothetical proteinBLASTP
649946509299hypothetical protein
6509265679588hypothetical protein
66688679111224integral membrane transport proteinQuickGO ontologyBLASTP
6837268887516hypothetical protein
6979970647849transposaseQuickGO ontologyBLASTP
7077771235459hypothetical proteinBLASTP
7164872139492hypothetical protein
7215973097939ribosylglycohydrolase secreted proteinQuickGO ontologyBLASTP
73784748331050secreted proteinQuickGO ontologyBLASTP
7491775876960secreted beta-lactamaseQuickGO ontologyBLASTP
75856768931038transcriptional regulatorQuickGO ontologyBLASTP
7689577314420transposaseQuickGO ontologyBLASTP
7731578271957IS1652 transposaseQuickGO ontologyBLASTP
7898379702720hypothetical proteinBLASTP
7983980690852noncomposite transposon transposaseQuickGO ontologyBLASTP
8084581165321integral membrane proteinQuickGO ontology
8160282441840transposaseQuickGO ontologyBLASTP
8351684259744hypothetical proteinBLASTP
8489385339447hypothetical protein
85336866431308flavohemoproteinQuickGO ontologyBLASTP
8664087311672hydrolaseQuickGO ontologyBLASTP
8790788632726endo-14-beta-xylanase secreted proteinQuickGO ontologyBLASTP
8907389465393insertion element transposaseQuickGO ontologyBLASTP
8948690043558aminoglycoside nucleotidyltransferaseQuickGO ontologyBLASTP