Pre_GI Gene

Some Help

Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:5443832 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
544383254450881257septum site-determining proteinQuickGO ontologyBLASTP
54450855445480396septum site-determining proteinQuickGO ontology
54454825445877396septum site-determining proteinQuickGO ontology
544589654472331338secretory proteinQuickGO ontologyBLASTP
54472435448193951integral membrane proteinQuickGO ontologyBLASTP
54482135449115903integral membrane proteinQuickGO ontologyBLASTP
54493785449575198integral membrane proteinQuickGO ontology
54495785450174597secreted proteinQuickGO ontology
54502075450785579secreted proteinQuickGO ontologyBLASTP
54507945451405612secreted proteinQuickGO ontologyBLASTP
54515035452318816integral membrane proteinQuickGO ontology
545252654536231098araC family regulatory proteinQuickGO ontologyBLASTP
54537745453983210integral membrane proteinQuickGO ontology
54539935454598606secreted proteinQuickGO ontologyBLASTP
54545915455127537hypothetical proteinBLASTP
54553155455980666lipoproteinQuickGO ontologyBLASTP
54562215456883663lipoproteinQuickGO ontologyBLASTP
545689254579021011secreted proteinQuickGO ontologyBLASTP
54580195458891873oxidoreductaseQuickGO ontologyBLASTP
54589945459911918transcriptional regulatorQuickGO ontologyBLASTP
54599085460726819hypothetical proteinBLASTP
546075754619501194hypothetical proteinBLASTP
546301254643371326ATP-binding proteinQuickGO ontologyBLASTP