Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:3893187 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
389318738944701284hypothetical proteinBLASTP
38944673894697231hypothetical proteinBLASTP
389470638958661161hypothetical proteinBLASTP
38961973896718522hypothetical protein
38972413897840600hypothetical proteinBLASTP
38978373898616780hypothetical proteinBLASTP
38986133899089477hypothetical proteinBLASTP
38990863899751666hypothetical proteinBLASTP
389982339023452523large ATP-binding proteinQuickGO ontologyBLASTP
390238139045012121hypothetical proteinBLASTP
390486939060411173DNA-binding proteinQuickGO ontologyBLASTP
39060583906801744hypothetical protein
39072693908108840transposaseQuickGO ontologyBLASTP
390852039101391620proteinase secreted proteinQuickGO ontologyBLASTP
391025239114571206DNA polymeraseQuickGO ontologyBLASTP
391161039148793270integral membrane protein with kinase activityQuickGO ontologyBLASTP
391502739178852859probable DNA topoisomerase IQuickGO ontologyBLASTP