Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:3138905 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
313890531401311227cytochrome P450QuickGO ontologyBLASTP
31401843140657474hypothetical proteinBLASTP
31407603141644885hydrolaseQuickGO ontologyBLASTP
31418053142107303membrane proteinQuickGO ontology
31421233142482360hypothetical proteinBLASTP
314252831440421515sugar transport proteinQuickGO ontologyBLASTP
314572631470901365secreted proteinQuickGO ontologyBLASTP
31471183147951834hypothetical proteinBLASTP
314798531490491065ABC-transport protein ATP-binding componentQuickGO ontologyBLASTP
31490583149945888integral membrane transport proteinQuickGO ontologyBLASTP
31499383150744807integral membrane proteinQuickGO ontologyBLASTP
315112531533952271probable secreted penicillin-binding proteinQuickGO ontologyBLASTP
31533893153709321molecular chaperoneQuickGO ontologyBLASTP
31538703154226357GroES-family molecular chaperoneQuickGO ontologyBLASTP
31542503154582333membrane proteinQuickGO ontologyBLASTP
31546773155144468hypothetical proteinBLASTP
3155187315527387tRNA-LeuQuickGO ontology
31552903155892603hypothetical proteinBLASTP
31559393156343405secreted proteinQuickGO ontologyBLASTP
31565013157238738ribonuclease PHQuickGO ontologyBLASTP
31573153157548234hypothetical proteinBLASTP
315770731590021296PTS transmembrane componentQuickGO ontologyBLASTP
315922931604791251PTS transmembrane componentQuickGO ontologyBLASTP
31605743161326753hypothetical proteinBLASTP
31615313161698168hypothetical protein
31617473162697951cysteine synthaseQuickGO ontologyBLASTP